SARMs or Selective Androgen Receptor Modulators are around since the beginning of the 1990s and during this time they were initially presented in mainstream science. Now, it can’t be said that this period saw the evolution of these compounds. Earlier, steroidal SARMs had been utilized for curing many kinds of diseases that include hypogonadism, cancer, osteoporosis and several other diseases that affect your muscle as well as bone wasting. These compounds leave its strong influence on your muscle building because of its attraction to one receptor and this attraction causes a chemical reaction in your body which is more powerful.
In the phrase “Selective Androgen Receptor Modulators” androgen means one class of hormones which act as ligands and they bind to the cellular androgen receptors. This androgen receptor is linked to a complicated signal transduction way which finally results in a larger expression of particular genes. Now, if you wish to know it in simple terms, then androgens are hugely helpful in building muscles. All the prohormones and anabolic steroids supply their muscle building characteristics via this binding process to the androgen receptor. SARMs supplement intend to provide similar kinds of influences like anabolic steroids but they are more selective regarding their actions.
Can females take them?
Women who are aged above 21 will have identical effects like men when they take these compounds. Actually, several studies proved that these compounds are equally beneficial to women when the matter comes to producing lean muscle and lessening fat. Unlike steroids or testosterone-pumped prohormones, these compounds are gentler and take an effectual approach. These compounds produce results slowly but they are quite safe, unlike anabolic steroids. There are some stackable SARMs that work fine for women and these compounds are particularly designed for the use of women. One among many packages that are fine for women comprises of S4, MK-2866, and GW.
These three compounds work wonders for the females and that too with very little or no negative side effects. However, the dosage for women is much lesser compared to the dosages for men. The testosterone-increasing SARMs have some side effects for women like they can develop unpleasant physical changes and can cause virilization in women. A woman who has increased testosterone dramatically may notice some changes, like acne, deepened voice, hair loss, menstrual problems, male hair growth etc. There are some women who prefer a product which is only anabolic in nature but does have androgenic properties and so it doesn’t upsurge the production of testosterone.
Some well-known compounds
There are many SARMs supplements and here are mentioned four chief SARMs that are helpful to fitness enthusiasts, bodybuilders, and athletes. They are:
- LGD-4033 – This supplement is powerful and non-steroidal bodybuilding compound and it lessens body fat and improves lean muscle mass.
- MK-2866 (Ostarine) – This supplement is superb for increasing lean body mass plus recomping.
- RAD140 – This is viewed as the most exciting of all SARMs. It produces muscle building impacts and also cures Alzheimer’s disease.
- S4 (Andarine) – This supplement cures osteoporosis and doesn’t produce the growth of prostate plus other secondary sex organs.
Other supplements like Cardarine (GW 501516) and SR9009 are generally grouped with SARMs but they are a little different.